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Experimental-theoretic rationale and hardware-software device of application of Raman-fluorescence medical technologies in dentistry were performed. High-sensitive and high-specific express methods of caries and demineralization level of hard tooth tissues diagnostic, species indication of germs and express determination of its sensitivity to medications, verification of medications and drugs, malignant and benign neoplasms express diagnostic were presented. Wide range of method's clinical-diagnostic capabilities and of presented domestic hardware-software complex of Raman fluorescence diagnostic are recommended for clinical application.

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