Background: Intraocular pressure (IOP) is an eye parameter of fundamental importance for the diagnosis of several eye conditions, including glaucoma, ocular hypertension, uveitis and trauma. This study aimed to evaluate the difference between IOP measurements taken by a Goldmann Applanation Tonometer and those taken by -care Tonometer. Methods: this cross sectional study comprised 180 eyes from 90 subjects males and females with age ranged between 16:62 years old. All patients in this study underwent Full history and full ophthalmic examination and assessment of visual acuity: Uncorrected visual acuity (U.C.V.A.), best corrected visual acuity (B.C.V.A.), Refraction using NIDEK Auto-Refractometer-Keratometer, anterior segment examination by slit-lamp biomicroscopy, Intraocular pressure (IOP) measurement using Goldman Applanation Tonometer (Haag -Streit At 900˚ Swiss Made) and Handheld non-contact icare IC100 , fundus examination (including posterior vitreous, disc and macular examination). Results: There were highly significant differences between IOP measurements taken by I care and IOP measurements taken by Goldmann Applanation Tonometer (p <0.001); the mean of IOP measured by I care (15.73±3.58) was significantly lower than the mean IOP measured by Goldmann (17.35±1.99), Conclusion: the I-care tonometer almost constantly produces IOP measurements lower than those of the gold standard Goldmann Applanation Tonometry.