Improve the results of resection of the pancreas in chronic pancreatitis. Methods: The clinic resection of the pancreas in 86 patients. Male-70 (82%) , women-16 (18%). The average age of 50,47 4 years. One month after surgery, with the presence of inflammatory infiltrate in parapankreal tissue, conducted Regional intra-arterial infusion of the celiac artery or gastroduodenal hydrocortisone 50 mg or 5-ftoruracil at a dose of 0.5 grams per day in order to arrest the inflammatory process in the pancreas and tissues for parapankreal tissue 5e7 days. Results: The first group included patients with PDR-12, distal resection-17 and intraparenchymal resection-48. The second group included patients with intraparenchymal resection using a sealing seam pankreatoenteroanastomosis loop or stomach-9, including 5 patients received intraarterial infusion of hydrocortisone or 5-fluorouracil. Mortality in the first group was 4%. Complications occurred in 28% of patients, mainly in the first group. When analyzing the reasons for the formation of complications, it turned out that they include patients with a loose structure of the pancreas, as well as in cases of inflammatory infiltration parapankreal fiber and the presence of cold abscess.Suture failure PEA is found in 2 patients, abscesses in the area of PEA and subhepatic space in 9 patients, a violation of evacuation after pPDR in 8 patients, and bleeding from the branches of GDSs and splenic artery aneurysm in 3 patients. Conclusions: 1) The use of intraparenchymal pancreatic resection produces fewer complications than gastropankreatoduodenalnoy resection ; 2) Complications arise in cases where there is inflammation in the papapankreal tissue 3) The use of complicated cases of chronic pancreatitis sealing the free end of the intestinal loop is not accompanied by the emergence of insolvency pancreatic and intestinal anastomosis.

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