Eymeriosis (coccidiosis) is a protozoal disease of a poultry characterized by inhibition, loss of appetite, thirst, diarrhea, often with blood, anemia, nervous phenomena. Diseases are registered in the world everywhere, including in Ukraine. Regardless of its type eymeriosis is one of the most serious technological diseases of farm birds in developed countries. Sick animals excreted with oocysts, which are the source of invasion, and contaminated by them feed, water, litter, equipment of livestock buildings, objects of care, etc. are the factors of transmission. Infection with coccidia occurs in an elementary way by swallowing an oocyst with water or food. The results of the study of the des-invasive effect of the Bi-des preparation on oocysts of chicken eimery are presented. In the formulation of the proposed disinfectant, as ADR included: PGMG-hydrochloride and triamine and auxiliaries substances – cocamidopropyl-betaine and glutamic acid as well. Due to which this pharmaceutical combination has a cleansing effect. Researches of the effect of the «Bi-des» preparation on the process of sporulation of the oocyst E. tenella was carried out at concentrations of 1, 2 and 3% with exposition of one, two, three and four hours. It was found that the preparation of 1% concentration with  exposition of three and four hours caused the death of almost half of the oocyst eimery (44.98 and 47.9%). Sufficiently high oocystocidal effect (62.7–79.9%) were found at 2% disinfectant concentration with different exposition regimes. 3 hours exposition caused 100% lysis oocyst eimeria of chicken. It was established that using  the preparation caused visible destructive changes of morphology of the simplest and led to the static effect on the sporulation of the oocyst.

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