Acids. -(TYUNEVA, I. V.; FILIMONOV, S. I.; SOLOV'EV, M. Y.; KRAVCHENKO, D. V.; BALAKIN, K. V.; SKORENKO, A. V.; DOROGOV, M. V.; Izv. Vyssh.

Fused pyrimidine derivativesFused pyrimidine derivatives R 0515 Synthesis and Properties of Novel Sulfonamides Containing 1,3-Dimethyl--1H-quinazoline-2,4-dione Fragment. -Combinatorial synthesis concerning a library of novel potentially bioactive compounds which containing a sulfonamide and a dimethylquinazolinedione fragment is described. -(KHAKHINA, M. Y.; KORSAKOV, M. K.; BALAKIN, K. V.; SKORENKO, A. V.; KRAVCHENKO, D. V.; SOLOV'EV, M. Y.; PROSKURINA, I. K.; DOROGOV, M. V.; Izv. Vyssh. Uchebn.

Fused pyridine derivatives R 0450 Synthesis, Structure and Properties of Imide Derivatives of Vicinal Pyridinedicarboxylic Acids -[recyclization of anhydrides of pyridinedicarboxylic acids with amines and amino acids]. -(SOLOV'EV, M. Y.; FILIMONOV, S. I.; BALAKIN, K. V.; DOROGOV, M. V.; Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol. 47 (2004) 3, 38-42; Yaroslavskii gos. pedagog. univ. im. Ushinskogo, Yaroslavl', Russia; Russ.) -Mischke 23-146

No abstract

Basis of 2-Amino-5-bromopyridine-3-sulfonylchloride. -Substrate (I) is used for the preparation of novel carboxylic acids (IV) and (XII), which on treatment with a variety of amines form libraries of type (X)(41 examples) and (XIV)(135 examples). The use of amines instead of ammonia allows the preparation of 175 previously unknown sulfonamides of type (II). At elevated temperature, acid (IV) is transformed to the new fused heterocycle (V). Reaction of (IV) with anhydride (VI) affords a novel heterocycle (VII) which reacts with various amines to derivatives of type (IX). -(DOROGOV, M. V.; SOLOV'EV, M. Y.; KRAVCHENKO, D. V.; BLYUMINA, M. V.; TKACHENKO, S. E.; IVASHCHENKO, A. V.; Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol. 48 (2005) 4, 112-118; Yaroslavskii gos. pedagog. univ. im. Ushinskogo, Yaroslavl', Russia; Russ., Abstr. Eng.) -Y. Steudel 43-180