A new triterpene saponin, named as 23-hydroxy-3α (9), was isolated from the leaves of Bauhinia variegata Linn. In addition, six fl avonoid compounds along with two cinnamic acid derivatives were isolated and identifi ed based on their chromatographic properties, and chemical and spectral data (ESI-high resolution-MS n , 1 H NMR, 13C NMR, 1 H-1 H COSY, HSQC, and HMBC). Compound 9 was found to be nontoxic (LD 50 ) and to have signifi cant anti-infl ammatory and antinociceptive activities. It also showed a slight antischistosomal activity.