ABSTRACTObjective: This report provides an overview and assessment of the School Dismissal Monitoring System (SDMS) that was developed by the Centers for Disease Control and Prevention (CDC) and the US Department of Education (ED) to monitor influenza-like illness (ILI)-related school dismissals during the 2009-2010 school year in the United States.Methods: SDMS was developed with considerable consultation with CDC's and ED's partners. Further, each state appointed a single school dismissal monitoring contact, even if that state also had its own school-dismissal monitoring system in place. The SDMS received data from three sources: (1) direct reports submitted through CDC's Web site, (2) state monitoring systems, and (3) media scans and online searches. All cases identified through any of the three data sources were verified.Results: Between August 3, 2009, and December 18, 2009, a total of 812 dismissal events (ie, a single school dismissal or dismissal of all schools in a district) were reported in the United States. These dismissal events had an impact on 1947 schools, approximately 623 616 students, and 40 521 teachers.Conclusions: The SDMS yielded real-time, national summary data that were used widely throughout the US government for situational awareness to assess the impact of CDC guidance and community mitigation efforts and to inform the development of guidance, resources, and tools for schools.(Disaster Med Public Health Preparedness. 2012;6:104-112)

Listening to music can affect cognitive abilities and may impact creative cognition. This effect is believed to be caused by music’s impact on arousal and mood. However, this causal relationship has been understudied. Furthermore, the strength of semantic knowledge associations has also been linked to creativity and provides an alternative hypothesis for increases in creative cognition. The relationship between music, mood, semantic knowledge, and creative cognition is not well understood. The present study consisted of two experiments. The first examined the relationship between music listening and creative cognition, the second additionally sought to examine whether the effect of music on semantic memory and/or mood are mechanisms that promote creative cognition. In the first experiment, participants completed 15 items of the Remote Associates Test of Creativity after listening to hip-hop music, classical music, and babble. In addition to replicating the first experiment, the second also measured mood and semantic memory. In both experiments participants displayed greater creativity after listening to music. Semantic memory retrieval was enhanced after listening to music, but creative cognition and semantic memory were not significantly correlated with mood. The findings show parallel, positive effects on creative cognition, semantic retrieval, and mood when subjects listen to music.

Recent advances have suggested that non-coding miRNAs (such as miR-21, miR-27, miR-145, miR-155, miR-365, miR-375 and miR-494) may be involved in multiple aspects of oral cancer chemotherapeutic responsiveness. This study evaluated whether these specific miRNAs are correlated with oral cancer responsiveness to chemotherapies, including Paclitaxel, Cisplatin and Fluorouracil (5FU). Commercially available and well-characterized oral squamous cell carcinoma cell lines (SCC4, SCC9, SCC15, SCC25 and CAL27) revealed differing resistance and chemosensitivity to these agents—with SCC9 and SCC25 demonstrating the most resistance to all chemotherapeutic agents. SCC9 and SCC25 were also the only cell lines that expressed miR-375, and were the only cell lines that did not express miR-27. In addition, the expression of miR-375 was associated with the upregulation of Rearranged L-myc fusion (RLF) and the downregulation of Centriolar protein B (POC1), whereas lack of miR-27 expression was associated with Nucleophosmin 1 (NPM1) expression. These data have revealed important regulatory pathways and mechanisms associated with oral cancer proliferation and resistance that must be explored in future studies of potential therapeutic interventions.

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