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This study was performed to evaluate the usefulness of bone tracer 99m TC-MDP in detecting renal disorders by imaging of renal cortex for patients with cortical defect and estimation of split renal function (SRF) as compared with renal cortical imaging agent 99m TC-DMSA. In this study 23 patients (6 males, 17 females) with range age of 16y -75y (mean 45.6y ± 17.4y), and a total of 46 studies (using both 99m TC-DMSA and 99m TC-MDP per patient for left and right kidneys) were performed for detecting renal disorders. Both studies were performed within 48 hours between each other. SRF was calculated in all cases from renal uptake of the tracers into the region of interest by using computer acquired data of gamma camera. For detecting renal cortex abnormalities, all cortical scars and defects scars seen on 99m Tc-DMSA scan were also detected by 99m Tc-MDP.The results showed that the non visualized kidney on 99m TC-DMSA scan was also non visualized on 99m TC-MDP. Also, there was a high correlation between SRF values obtained from 99m TC-MDP and 99m TC-DMSA, where (p>0.01, r= 0.93 for left kidney and r=0.0.92 for right kidney).The similar SRF values of 99m TC-MDP and 99m TC-DMSA allow to use of 99mTC-MDP tracers for detecting both of bone and renal abnormalities.

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