Background: Adnexal masses are common lesions in women across the globe. This is also important for woman in Bangladesh. The incidence of adnexal malignancy ranks only after the carcinoma of cervix and endometrium. So their accurate and early diagnosis is necessary for design management and treatment protocol. Objective: The aim of the study is to assess the correlation between histopathological examination and ultrasonographic evaluation in making early and confirm diagnosis of adnexal masses. Methodology: Eighty four women with different ages having adnexal mass, diagnosed by ultrasonographic evaluations and followed by surgery were included in this study between january 12 to December, 14. The morphologic characteristics of the masses were evaluated with gray scale Ultrasonography (USG). Specimens were collected after surgical resection in a container containing 10% formalin. The specimens were processed by paraffin embedding method and stained by routine Haematoxylin and Eosin stain for microscopic examination. The results of this study were calculated by standard statistical formula. Results: Histopathological examination revealed that 68 masses (80.95%) were benign, two (2.38%) were borderline malignant, and 16 (19.05%) were malignant. USG enabled correct diagnosis of 63 of the 68 benign masses (92.65%) and all 16 malignant masses (100%). Conclusion: There is a correlation between histopathological examination and ultrasonographic evaluation of adnexal masses in most cases. Therefore the imaging analysis of internal architectural appearance by USG and histopathological examination increases the specificity in the diagnosis of adnexal masses.

Breast cancer stands first in the incidence of malignancy in women. Enormous studies have been conducted worldwide regarding hormone receptor status in breast cancer. The study was done in the department of pathology in Khulna Medical College, Khulna to compare the clinicopathologic features with four breast cancer subtypes defined by immunohistochemistry (IHC) expression of estrogen receptor (ER) or progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her2): ER/PR+, Her2+; ER/PR+, Her2_; ER/PR_, Her2+; and ER/PR_, Her2_ and to evaluate hormone receptor status in breast cancer to estimate a patient's response to endocrine therapy and their prognosis for better clinical outcomes. It is a retrospective observational study from 1st January, 2015 to 31st December, 2017. A total 378 invasive breast cancer subjects who underwent diagnostic tests for hormone receptors status were included in this study. Clinical and pathologic features and survival of the four subtypes were compared. Data of oestrogen, progesterone and human epidermal growth factor receptor 2 expression statuses was analyzed. Overall record of 378 patients was studied of whom 43% were identified to have positive hormone receptor status. The age of the patients ranged from 24 to 86 years with 65% in 25-50 years, 30.8% in 51-75 years and 4.08% in 76- 100 years. Fiftyeight percent were diagnosed as Stage III, 37% Stage II and 5.3% Stage IV. Those diagnosed with oestrogen receptor (positive status) were 10.7%, human epidermal growth factor receptor 2 over-expression 8.7%, oestrogen/progesterone hormone receptor positivity 51% and 23.4% patients were positive for all the three receptors. The triple negative subtype has the worst overall and disease free survival. Faridpur Med. Coll. J. Jan 2019;14(1): 8-12

Abstract:Malaria caused by vivax is more common than those caused by falciparum. We report here a patient of vivax malaria presented with tender hepatomegaly. A 30 year old male from a rural area was admitted with high grade irregular fever for 5 days with severe right hypochondriac pain for 2 days. Patient was toxic and agonizing with pain. He had tender hepatomegaly. His cardiovascular and respiratory examination findings were normal. ICT for malaria and blood film revealed presence of P. vivax. His hepatic enzymes and viral markers were negative and ultrasonogram of hepatobiliary system excluded features of hepatitis or any abscess cavity. Echocardiogram showed no cardiac abnormality. Presence of tender hepatomegaly in the absence of other co-morbidity is rare in vivax malaria and not well documented in adults, which makes this presentation.