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The present article systematically gives a comprehensive review of current development of benzofuran-based compounds as antimicrobial agents and the perspectives that they hold for future research.

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A convenient method for the synthesis of tritium-labeled brassinosteroids with very high specific activity is reported. A 3 H-labeled 24-epicastasterone was isolated in high yield (40 mCi), radiochemical purity (>97%) and a specific activity up to 99 Ci mmol À1 . The labeling strategy was designed to employ a radiolabeling step at the late stage of the synthetic sequence.