Objective: Prediabetes is a dysglycemic state and is associated with subtle myocardial injury and dysfunction. We evaluated atrial conduction times (ACTs) and atrial electromechanical delays (EMDs) in prediabetic patients with coronary artery disease (CAD). Methods: In the present study, we recruited 128 consecutive patient candidates (40 euglycemic, 48 prediabetic, and 40 diabetic patients) for coro- nary artery bypass grafting. ACTs were measured using tissue Doppler imaging (TDI). The time intervals between the beginning of the P wave in the surface electrocardiogram and the peak of the a¢ wave in TDI (PA) in the septal and lateral mitral annuli and the lateral tricuspid annulus were measured and termed as “septal PA,” “lateral PA,” and “right ventricular (RV) PA,” respectively. The differences between lateral and septal PA, septal and RV PA, and lateral and RV PA were termed as “left intra-atrial EMD,” “right intra-atrial EMD,” and “inter-atrial EMD” respectively. Results: Septal PA, lateral PA, RV PA, left and right intra-atrial EMDs, and inter-atrial EMD were not statistically different between these three groups. Furthermore, multivariable linear regression models, adjusted for potential confounders, showed that glycemic state was not associated with ACTs, left and right intra-atrial EMDs, and inter-atrial EMD. Conclusion: There were no significant differences between the euglycemic, prediabetic, and diabetic patients with CAD regarding ACTs and atrial EMDs.

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Background: Vitamin D deficiency is one of the most common nutritional deficiencies. Cardiovascular disease patients are also prone to this condition. Recently, a relationship between vitamin D deficiency and cardiovascular diseases has been suggested. This study aims to compare the relationship between ventricular systolic function and vitamin D deficiency. Methods: This study investigated patients without obvious coronary artery disease between 2020 and 2021. First, vitamin D levels were measured in the patients. Then, they were divided into two groups based on a 30 ng/dl cut-off point. All patients underwent echocardiography and ventricular systolic function parameters were evaluated and compared. Results: In this study, 27 patients with normal vitamin D levels and 47 patients with vitamin D deficiency entered the study. There was no significant difference in demographic variables and underlying diseases between these two groups. There was no significant difference between left ventricular (LV) systolic function parameters including ejection fraction (EF), and LV end-systolic/diastolic volume. No significant difference was also observed between right ventricular (RV) systolic function parameters including Tricuspid Annular Plane Systolic Excursion (TAPSE), RV fractional area change (RVFAC), Right ventricular systolic velocity (RVSM) in tissue Doppler echocardiography as well as RV diastolic parameters such as A, E, E´, deceleration time (DT), right atrial volume (RAVi) as a precursor of right ventricular systolic dysfunction groups. Conclusion: Based on the results of this study, there is no relationship between vitamin D levels and ventricular systolic dysfunction.

Aims: The Coronary Slow Flow Phenomenon (CSFP) is a syndrome which according to normal or near normal angiography findings is characterized by delayed progression of the injected contrast medium through the coronary vessels. The causes of this disease are unknown. Therefore, the identification of the disease’s pathogen, an effective cure and the long-term prognosis of these patients is still in need of more research. This research attempts to analyze and compare the systolic and diastolic function of the left and right ventricle in people affected by primary Slow Coronary Flow and Normal Coronary Flow. Methods and Results: This case-control study was conducted with the participation of 44 patients undergoing coronary angiography in Qazvin’s Bu Ali Sina Hospital in 2017. The patients were divided in two groups of primary Slow Coronary Flow (33 people) and Normal Coronary Flow (11 people) and the systolic and diastolic function of the left ventricle and the systolic function of the right ventricle was analyzed and compared between the two groups. The frequency of left ventricular systolic and diastolic dysfunction and right ventricular systolic dysfunction was similar and no significant statistical difference was seen between the two groups. Conclusion: In this research the frequency of left ventricular systolic and diastolic dysfunction and right ventricular systolic dysfunction was similar and no significant statistical difference was seen between the two primary Slow Coronary Flow and Normal Coronary Flow groups. Keywords: left ventricular systolic function, left ventricular diastolic function, right ventricular systolic function, Coronary Slow Flow