In the rapidly changing world of health care, business, organisations  and industries focus on maximising the potential benefits of workforce, products and services. The purpose of the study is to explore the concept of organisational citizenship  behaviour and the factors that influence on OCB. Various studies found the connection  between OCB and effective  functioning  of  employees.  Many  factors  affect  personal  behaviour,  but  this  study  focuses  on  exploring  the relationship between affective disposition, organisation climate, organisational commitment and OCB among health professionals (N=400). This study also investigated the association of affective disposition, organisation climate, and organisational  commitment  as  a  predictor  of  organisational  citizenship  behaviour.  The  approach  of  this  study  was quantitative.  The  sample  of this study consist  of health professionals  (N=384),  having  an age range of 30-50  years.  A standardised questionnaire was used to measure dispositional affect, organisation climate, and organisational commitment and  OCB.  Participants  were  assured  of  confidentiality  and  instructed  to  choose  their  opinion  without  any  hesitation. Results revealed the predictive association of affective disposition, organisation climate, organisational commitment with OCB (F (3,396) = 249.195, p<.01).  In view  of our result, we prescribe  that it is vital to improving  the workplace  to empower specialists to advance their best and to decrease workplace disputes and crises. Employees who influence an organisation positively ought to be perceived and rewarded.