Systemic Lupus Erythematosus (SLE) is a multisystem auto-immune disease with wide spectrum of clinical and immunological abnormalities including development of auto-antibodies against DNA and other nuclear antigen. All organ tissues may be involved but the skin, joints, heart, nervous system and kidneys are most commonly affected. Clinical evidence of renal disease occurs in 40 to 75% of patients with SLE. The persistent proteinuria is the most frequent sign of the LN (Lupus Nephritis) and occurs in 70% of patients. A study was done involved 30 patients of Lupus Nephritis hospitalized in the