Authors describe the case of a patient with breast cancer and multiple myeloma as the second metachronous disease responsible for spinal cord compression. Synchronous occurrence of bone marrow breast cancer disease and multiple myeloma has not been described in the literature, as in this case. By presenting this case, we point to possible association between both diseases and the possible factors involved in the development of second malignant disease.

Melorheostosis is a rare entity belonging to the group of sclerotic bone dysplasias. Described for the first time in 1922 by Leri, it remains imperfectly known as clinical presentations are highly variable, and the etiological diagnosis is not fully elucidated. We report a case of polyostoticmelorheostosis for which radiological investigations were complete, in order to study this disease.

It is known that cervical spine involvement occurs in over half of patients with rheumatoid arthritis (RA). This involvement is over 70% in Tunisia. The majority of our patients are seen at Ranawat's stage III with spinal cord injury. We report a series of 28 patients treated in our institution for RA with atlantoaxial dislocation with several degrees of spinal cord injury (Ranawat's stage II and III). Even though overshadowed by major impairments related to severe peripheral joint disease, 60% of our patients presented a good functional result at the average of 10 years follow up.

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