This study was carried out during 2018/2019 and 2019/ 2020 seasons. On Valencia orange trees are grown in al kawamil orchard at the faculty of agriculture, sohag university, where the soil texture is sandy. The selected trees had the same vigor. This study aimed to throw some light on the effect of single and combined applications of some antioxidants (300 ppm ascorbic and 300 ppm salicylic acids), 1% magnesium and a mixture of micronutrients (300 ppm Fe, 200 ppm Zn, 200 ppm Mn) on some vegetative growth characters, fruit set %, fruit retention%, tree nutritional status, number of fruits per tree, yield and physical and chemical characteristics of fruits. Selecting the best-combined treatment from these antioxidants, magnesium and micronutrients responsible for gaining an economical yield is considered another target.Single and combined applications of these compounds were very effective in enhancing Main shoot length, shoot thickness, leaf area, fruit set %, Fruit retention%, nutrients in the leaves (N, P, K, Mg, Zn, Fe and Mn), Number of fruits per tree, yield as well as physical and some chemical characteristics of the fruits in relative to the check treatment.The best results about yield quantitively and qualitatively of Valencia orange trees were obtained when the trees received three sprays (growth start, just after fruits setting and one month later) of a mixture containing 300 ppm salicylic acid, micronutrients and 1 % magnesium sulphate).