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Among the most frequent gynecological operations conducted is the hysterectomy. Objective: To determine the outcome of TLH in benign uterine pathology of up to 12-week size uterus. Methods: It was a prospective case series carried out at Obstetrics and Gynecology department of Memon medical institute hospital, Karachi from January 2019 to January 2021. All patients who underwent laparoscopic hysterectomy secondary to benign utero- ovarian pathology were consecutively enrolled. Demographic characteristics of the patients along with the presence of co-morbidities, hospital admission details, surgical procedure and intra and post-operative complications were noted. The surgery performed with similar technique in all cases. If patients were deemed to be fit for release after 48 hours following surgery, they were discharged. The postoperative follow-ups were performed at 10th, 30th, and 3 months. Results: Of 50 patients, the mean age was 50.5 years. The main indication of hysterectomy is adenomyosis diagnosed in 20 patients. There were 4 laparoscopic assisted vaginal hysterectomies and 46 were total laparoscopic hysterectomies. History of previous laparotomies was observed in 12, previous cesarean and bilateral tubal ligation in 6 each, history of mesh repair of umbilical hernia in 4 while history of VP shunt was observed in 2 patients. Eight patients converted into laparotomy due to technical difficulty in controlling hemorrhage of uterine artery. Total rate of intra and post-operative complications was 40%. Conclusion: Laparoscopic approach for hysterectomy is a safe alternative to conventional hysterectomy for benign uterine pathology of up to 12 weeks size uterus.

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Objectives: The purpose of this study was to evaluate the neonatal outcomes in cord clamping and to find their correlation with different haematological parameters in neonates of Jinnah Postgraduate Medical Centre, Karachi Methodology: This was an observational study in which non-probability convenient sampling technique was used after taking ethical approval. The study was conducted on 342 pregnant women in the Obstetrics & Gynaecology ward of Jinnah Postgraduate Medical Centre, Karachi, from 1st July 2016 to 31st December 2016.All the pregnant women from age of 25 to 45 years and without any haemolytic disease, with previous spontaneous vaginal deliveries, with a singleton pregnancy diagnosed via ultrasound during the first trimester and presenting in the 3rd stage of labour with a gestational age of ≥ 37weeks were included in the study. Soon after the delivery of placenta, the uterus was massaged either by patient herself or by the caretaker. Neonatal blood samples were gathered by the researcher through venipuncture following expulsion of the fetus and 24 hours after it and sent to the pathology laboratory of Jinnah Hospital for analysis. Data were analyzed in SPSS Version 20. Descriptive analysis was done. Pearson and Spearman tests were applied to see the correlation of cord clamping time. P-value of < 0.05 was taken as significant. Results: A total of 342 pregnant females in their third stage of labor were selected for this study. No correlation existed between hemoglobin and hematocrit with cord clamping time (p-value 0.661) and (p-value 0.439) respectively. Weak positive correlation (p=0.002, r = 0.169) existed between billirubin levels with clamping time. No correlation was observed with cord clamping time and anemia, low hematocrit or polycythemia (p-value 0.422), (p-value 0.058) and (p-value 0.20) respectively while weak negative correlation (ρ = -0.221) existed between high bilirubin levels in neonates with increasing cord clamping time (p-value < 0.001). Conclusion: According to our study, no correlation exists between hemoglobin and hematocrit with cord clamping time but weak positive correlation was observed between billirubin levels with clamping time in seconds. Keywords: cord clamping; correlation; haematological parameters

Dengue fever is a deadly mosquito-borne viral infection. It is caused by the bite of female mosquito by Aedes aegypti and in some cases also by Aedes albopictus, infected with the virus. Dengue virus is RNA virus, which is single-stranded.