VD is responsible for the major cause of dementia in the younger women and the men under 90 years of age; AD is the leading cause of dementia in the elderly men and the women over 79 years of age in nursing homes, Shimane prefecture, Japan.

We investigated the use of the spatial ventricular gradient (VG) from vectorcardiogram (VCG) to determine whether significant repolarization differences were present in patients with WPW syndrome compared with normal subjects and also examined which VGparameter (i.e., elevation, azimuth, and magnitude) reflected the differences in repolarization properties during preexcitation. VG was calculated in 49 patients ofWolff-Parkinson-White (WPW) syndrome (group A: left-sided accessory pathway, n=29; group B: right-sided, n=20). Group N consisted of 607 normal subjects. In group A, the azimuth ofVG was significantly (p<0.01) greater than in groups B and N. In group B, the elevation of VGwas significantly (p<0.01) greater than in groups A and N. There were no significant differences in the magnitude of VGamonggroups. QRSduration was significantly (p<0.01) related with the elevation ofVG in group B. These findings suggested that VGis useful for spatial evaluation of repolarization abnormalities during preexcitation, which are related to the site of the accessory pathway. (Internal Medicine 34: 738-743, 1995)

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