BACKGROUND:Acute bacterial rhinosinusitis is one of upper respiratory tract infection that disturbs patient life and requires special consideration.AIM:To evaluate the efficiency of Ceftriaxone versus a high dose of Amoxicillin-clavulanic acid for the treatment of acute bacterial rhinosinusitis.PATIENTS AND METHOD:Observational retrospective study include120 patients of both sex classified into two groups equally conducted. G1 treated with Ceftriaxone 1 g intramuscular injection once daily while, G2 treated with oral Amoxicillin-clavulanic acid (875 mg/125 mg) twice daily for 3-4 days then, the outcome of treatment evaluated as a cure or failed at the fifth or fourth day of treatment.RESULTS:Significant cure response observed in Ceftriaxone treated patient’s P ≤ 0.05 and significant failure response observed in Amoxicillin-clavulanic acid-treated patients when groups compared with each other. About gender and age groups, no significant differences in number between group 1 and 2 P ≥ 0.05.CONCLUSION:Ceftriaxone found more effective in the treatment of acute bacterial sinusitis than Amoxicillin+ clavulanic acid. Amoxicillin+clavulanic acid associated with more male failure cases recorded than female.
Background. Methyl methacrylate (MMA) is one of the widely used organic monomers in dentistry. It may cause multiple adverse reactions, ranging from allergic reaction to systemic toxicity. Dentistry students are exposed to MMA in an acute manner; however, the concentration of its vapor cannot be estimated well. Objectives. The aim of this study was to evaluate the effect of acute MMA vapor inhalation on the pulmonary function of dental students, both smokers and non-smokers. Material and methods. Thirty-eight male dental students were divided into 2 groups (group 1-smokers and group 2-non-smokers). The lung function parameters of the students were tested with a spirometer during their ordinary training work in a prosthodontics laboratory, before contact with MMA and immediately after it. The lung function test was performed using a standard protocol. The students were asked not to use any perfume or aromatic overlaps for a period of 24 h before starting the tests. Results. The researchers noted a statistically significant decrease (p ≤ 0.05) in forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), peak expiratory flow (PEF), forced expiratory flow at 25-75% of the pulmonary volume (FEF25-75), and forced expiratory flow at 25% (FEF25) and 50% (FEF50) of the pulmonary volume in smokers and non-smokers by comparing the pre-and post-work tests. Conclusions. Acute inhalation of MMA vapor induced a moderate restriction of pulmonary function in dental students, both smokers and non-smokers, during their routine prosthodontics laboratory training work. No differences in the results of the pulmonary function tests between smokers and non-smokers were observed.
BACKGROUND: Diabetic foot infection is a major cause of patient disabilities and lowers limb amputations, with high treatment costs and hospitalisation requirements. AIM: Aim of this study was to evaluate surgical wound care plus antibiotic effects in the treatment of mild and moderate diabetic foot infections. METHODS: This retrospective study involved 60 patients with diabetic foot infections with or without osteomyelitis. The patients were categorised as group 1 mild and group 2 moderate. Both groups were treated using local wound debridement and the systemic administration of antibiotics. Group 1 (16) patients were treated with two regimens of oral antibiotics in two regimens, A (amoxicillin/clavulanate + metronidazole) and B (clindamycin + metronidazole), for 10-14 days. Group 2 (42) patients were treated with oral plus intravenous antibiotics in two regimens, A (ampicillin + cloxacillin + metronidazole) and B (lincomycin + metronidazole), for 6 weeks. The patients followed-up with local wound care specialists for 3 months to evaluate the treatment outcomes (cure, improvement, or failure). RESULTS: Group 1 had an 80% cure rate under regimen A and a 100% cure rate under regimen B. Group 2 regimen A patients had a 61.5% cure rate and 11.53% improved, while regimen B patients had a 68.75% cure rate and 12.5% improved. Failure in both regimens was 23.8% in 20 patients with osteomyelitis, while 35% were cured and 20% improved during the study period. CONCLUSION: Local surgical wound care for 3 months with antibiotic regimens for 6 weeks resulted in good response and cure rates, with lower costs and fewer instances of hospitalisation. Intravenous lincomycin and oral metronidazole achieved higher cure responses for moderate diabetic foot infections.
BACKGROUND: Oroantral fistula (OAF) is a pathological communication between maxillary sinus and oral cavity, which treated by various surgical methods including buccal flap and associated with post-operative discomfort and relatively long healing period. AIM: The objective of the study was to evaluate the effect of 0.2% hyaluronic acid (HA) gel on the healing period after surgical buccal flap treatment of OAF. METHODS: The records of 20 patients of both genders included and reviewed retrospectively. Ten patients treated with topical 0.2% HA gel while the other 10 patients treated without it. Patients healing process followed up for suture removal appointment. RESULTS: Statistically significant p ≤ 0.05 decreases in healing period when we compare patients treated with topical HA gel and those without topical HA gel. CONCLUSION: The use of topical HA gel may have advantages for soft-tissue healing and decrease healing period for patients has OAF treated with surgical buccal flap.
Deep venous thrombosis (DVT), which is the formation of a blood clot (thrombus) in the veins, is a life-threatening condition caused mainly by vascular injuries, immobility, and hypercoagulation. 1 It can complicate the outcomes of patients who have undergone orthopaedic surgeries, such as for a total knee replacement or total hip replacement, especially in elderly patients who are more prone to long periods of immobility after surgery and injury. 2,3 Falck-Ytter et al 4 estimated a 5%-22% DVT incidence following total knee replacement surgery owing to the increasing numbers of such surgeries and the advanced age of the patients. Fortunately, DVT is a preventable complication, and many guidelines have been suggested to lower its incidence. 5 The prevention of DVT following orthopaedic surgery is based significantly on pharmacological prophylactic treatments, such as anticoagulant drugs, the most commonly used one of which is low-molecular-weight heparin (enoxaparin). 6 Enoxaparin indirectly
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