In the World Health Organization classification system, mucinous tubular and spindle cell carcinoma of the kidney (MTSCC-K) has been described as a rare pathologic subtype of renal cell cancer. This tumor is supposed to have good prognosis, though follow-up data are limited due to rarity of tumor. MTSCC-K is a rare variant of renal cell carcinoma with female predominance and favorable prognosis. We report our experience with a case of mucinous tubular spindle cell carcinoma involving the kidney. A 61-year-old female presented with a palpable left renal lump of 12 cm in size. Computed axial tomography scan revealed a well-circumscribed mass of 11 cm involving the lower pole of the left kidney. She underwent left open radical nephrectomy. The cut section revealed a well-circumscribed tumor with yellowish-white variegated areas measuring 11 cm × 8 cm × 7 cm. Histopathological diagnosis of mucinous tubular spindle cell carcinoma of the kidney was given, and the patient responded well after the treatment. An accurate diagnosis may have an impact on prognostication of tumor and understanding the biology of the tumor. Thus, the clinicians should be aware of this rare disease for prompt diagnosis.

Background: Urinary tract infections (UTIs) are one of the most common infections. For treatment of UTIs, there are limited antibiotics due to increased resistance among uropathogens. Two older antibiotics; Nitrofurantoin and Fosfomycin have become novel oral therapeutic options against uropathogens. Aim of the study was to identify UTI causing micro-organisms and evaluate in-vitro activity of nitrofurantoin and fosfomycin against most common isolated organism (E. coli).Methods: Results of urine samples culture and susceptibility testing over a period of 1 year were analysed and included in this study.Results: Micro-organisms were isolated from 568 urine samples. Most commonly isolated organism was Escherichia coli (40.50%), followed by Klebsiella spp. (20.07%) and Staphylococcus spp. (17.07%). Susceptibility of E. coli to nitrofurantoin and fosfomycin was 91.74% and 65.65% respectively. Conclusion: Good activity of nitrofurantoin and fosfomycin against E. coli indicates that these two drugs are potential therapeutic alternatives for urinary tract infections.

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Background: Dengue virus infection is fastest spreading, mosquito borne viral disease in the world with an estimated 3.9 billion people at risk of infection. Dengue is notifiable disease in India, but real number of cases could not be identified many times due to the under-reporting or misdiagnosis of cases. The purpose of the present study was to estimate prevalence of dengue viral Infection among suspected patients attending a tertiary care centre.Methods: Blood samples from suspected patients were collected over a period of 1 year and were analysed for dengue virus specific IgM antibodies and NS1 antigen by immuno-chromatographic method.Results: Total 196 samples were tested out of which 43 (21.43%) showed laboratory evidence of dengue. Maximum samples were received during monsoon and post-monsoon period. Dengue sero-positivity was found to be highest in post monsoon period i.e., October-November. Maximum dengue positivity rate was found in the age group of 16-45 years.Conclusions: For estimation of true burden of dengue in India and its geographical mapping to control further disease transmission; laboratory-based active surveillance systems are required along with passive surveillance and control programs.

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