suboptimal or excessive in about 32-45% of cases [3]. Further, more than three-quarters of patients on tablet LT4 therapy complain about poor quality of life (QoL) and low treatment satisfaction [4][5][6].There are numerous possible causes of poor control of hypothyroidism. LT4 has a narrow therapeutic index, i.e. the difference between the minimum effective concentration and the minimum toxic concentration
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.