Recent studies of the peritoneal cavity environment in endometriosis demonstrate quantitative and qualitative changes in the cells responsible for cell-mediated immunity. Such changes may have led to disturbances in the surveillance, recognition, and destruction of misplaced endometrial cells and might have, in fact, brought about the disease. The aim of the study was to assess CD95 (Fas) expression on (activated) peritoneal fluid (PF) macrophages, as well as to ascertain soluble Fas (sFas) concentration in the PF of endometriosis patients, as compared to the nonendometriotic group. The concentration of leukocytes in the PF, the percentage of cells expressing CD45+/CD14+, and the percentage of PF macrophages expressing the HLA-DR antigen were significantly higher in patients with stages I and II endometriosis. The percentage of Fas- (CD95+-) expressing macrophages was significantly higher in all stages of the disease, in comparison with controls. Moreover, the concentration of sFas in the PF of patients with moderate and severe endometriosis was significantly higher, as compared to the reference group. The high number of immune cells in PF in early stage endometriosis and their increased susceptibility to apoptosis confirm the role of the impaired peritoneal environment and immune defects in the development and progression of the disease.

It has been widely underlined that both gynaecological malignancies and urogynaecological disorders are often associated with high stress and have a negative impact on the quality of life and psychological well-being of women affected. Knowledge of the pelvic anatomy is crucial in recommending and carrying out the least harmful although successful treatment. Subsequent chemoradiation may also induce or exaggerate troublesome symptoms. The aim of the study was to establish the frequency of urogynaecological symptoms (stress urinary incontinence, urgency, pelvic organ prolapse) and to assess the impact of surgical treatment and additional oncological therapy: pelvic radiation, chemoradiation, chemotherapy, on the prevalence of pelvic floor dysfunctions (PFD) and lower urinary tract symptoms (LUTS) in patients suffering from gynecological malignancies. The study group consisted of 160 women, diagnosed with gynaecological malignancy, who underwent surgical treatment and additional adjuvant treatment as necessary. To establish the QoL and prevalence of PFD Urinary Distress Inventory-6 (UDI-6), Incontinence Impact Questionnaire 7 (II-Q7), King’s Health Questionnaire (KHQ) and the SF-36 Questionnaire were used. Herein, 69 patients reported urinary incontinence (UI) and 67 reported symptoms of pelvic organ prolapse (POP). After the six months follow-up UI was found in 78 patients, 25 patients showed de novo symptoms, 65 patients reported POP and 10 patients demonstrated de novo POP. Our data show that urogynaecological symptoms are not correlated with the type of malignancy, but with the extensiveness of surgery.

The aim of this study was to assess the effectiveness of vaginal native tissue repair (VNTR) on preexisting Lower Urinary Tract Symptoms (LUTS) in women with symptomatic pelvic organ prolapse (POP). Two hundred patients who underwent VNTR for symptomatic POP from January 2018 to February 2019 were followed up for 6 months. All patients underwent VNTR, but in the posterior compartment, the rectovaginal fascia was reconnected to the uterosacral ligaments and additionally sutured to the iliococcygeus fascia and muscle. To assess the severity and change in storage phase LUTS before and after surgery, all participants were asked to complete 3 questionnaires: the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), Urogenital Distress Inventory-6 (UDI-6), and Incontinence Impact Questionnaire-7 (IIQ-7). The data were assessed with Statistica package version 12.0, using Kalmogorow-Smirnoff, W Shapiro-Wilk tests. Furthermore, one-way analysis of variance was applied with post-hoc Tukey test. The study results indicate that the majority of patients with advanced POP suffered from various LUTS. Among storage symptoms, the occurrence of urinary incontinence (UI) and urgency decreased significantly after surgery. Moreover, ICIQ-SF, UDI-6, and IIQ-7 results showed statistically significant improvement in the impact of UI on the quality of life (QoL) in the vast majority of patients after surgery. VNTR is an effective way to treat not only anatomical, but also functional problems in such patients.

Aim The aim of the study was to develop and validate the semi‐quantitative brief food frequency questionnaire to assess the magnesium intake (Mg‐FFQ). Methods The developed questionnaire consists of 39 questions and it was validated in a group of 75 women aged 20‐30. The validity was assessed with reference to the 3‐day dietary record and the reproducibility was assessed for a period of 6 weeks. Results The Bland‐Altman index for the assessment of validity was 6.7% and for reproducibility—8.0%, while the kappa statistic indicated a slight and substantial agreement, respectively. The high reproducibility was confirmed by a high share of respondents correctly classified into tertiles (73.3%) and correctly classified into categories of adequate/inadequate intake (85.3%). Conclusion For the developed and validated Mg‐FFQ, a high reproducibility, accompanied by a satisfactory validity, was confirmed, so it may be used to assess the magnesium intake in the epidemiological studies in young Polish women aged 20‐30.

The article presents the course of the composite rotor blades tests. Object of study was designed in Institute of Aviation, new airfoil for gyroplane rotors and technology of manufacturing carbon rotor blades were made. When the test program was developed, we focused for special test to check not only typical rotor blades properties but also composite structures thereby technology of manufacturing. One of the basic rotor blades test is to determine the breaking force, which, taking into account the safety factor, cannot exceed the maximum centrifugal force occurring on the rotor blades during flight. The first step of rotor blades tests was static test, which gave us answer about stiffness in plane of low stiffness and torsional stiffness, it's very important properties related to vibrations. Another mechanical properties measured during tests were centre of gravity and mass moment of inertia in rotor blade. Next step was dynamic test-tracking and balancing verification. After static and dynamics, which has proper resultsgood balance and no vibration on the entire range of rotational speed-rotor blades can be use on fly object. After getting proper results of static and dynamic test next step was a specially prepared test, which defined the time needed for delamination to take place. During the delamination tests, the rotor blade was subjected to adequate loads that occur in horizontal flight. That kind of test is basis to determine service life of rotor blades.