The utilization of stone bananas is still very minimal, especially banana peels which will only end up as waste. Despite the fact that stone bananas are a fruit high in metabolites, they have numerous health benefits.The banana peels (Musa balbisiana Colla) was extracted with ultrasound-assisted extraction to determine the content of secondary metabolites, total fernol, antioxidant capacity using the DPPH and FRAP methods, as well as the potential for antigout activity in the extract. Ultrasound-assisted extraction is a less expensive, simpler, and more reliable alternative to traditional extraction methods. Musa balbisiana Colla banana peel extract contains alkaloids, saponins, tannins, steroid glycosides and phenols as secondary metabolites. The results obtained from determining the total phenol content was 397.50±0.41 GAE/g sample. Then the results of testing for free radical scavenging activity with the DPPH and FRAP methods showed IC50 values of 143.97±0.17mg/L and 151.08± 0.32mg/L, respectively. Meanwhile the antigout activity was obtained 27.95±0.08% which was greater than Alupurinol, so that Musa balbisiana Colla banana peel has the potential as an alternative compound to reduce uric acid levels.

In this study, Musa balbisiana Colla seeds were extracted using Ultrasonic Assisted Extraction method. it was found that seeds extract of Musa balbisiana Colla contained alkaloid, phenolic, saponin, tannin and steroid glycoside compounds by phytochemical test. Antioxidant activity was determined by 1,1-diphenyl-2- picrylhydrazil and ferric reducing antioxidant power method while allopurinol was used to determine non uric acid capacity of Musa balbisiana Colla seeds extract. The total phenolic content of Musa balbisiana Colla seeds extract was 375mg/mg gallic acid. Antioxidant activity test was carried out using 1,1-diphenyl-2- picrylhydrazil method and ferric reducing antioxidant power method with the result in the form of Inhibitory Concentration 50. Inhibitory Concentration 50 value of Musa balbisiana Colla seeds extract was around (94.27±0.22) mg/L by 1,1-diphenyl-2- picrylhydrazil method which was classified as a very strong antioxidant activity. Inhibitory Concentration 50 value of Musa balbisiana Colla seeds extract using ferric reducing antioxidant power method was around (409.91±2.35)mg/L which was classified as very weak antioxidant activity. Anti-uric acid activity of Musa balbisiana Colla seeds was higher than the synthetic anti-uric acid drug allopurinol, which was around 38.27% and allopurinol was about 2.80%. These results illustrate that the seeds extract of Musa balbisiana Colla have the potential material as an ingredient in treating diseases caused by gout.