Diagnostic treatment planning is crucial to achieve optimal success in oral rehabilitation, and this will be impossible without assistance of diagnostic imaging. For this reason, cone beam computed tomography (CBCT) was introduced and is known for its accuracy and variegated clinical importance. In current era, cone-beam tomography is aiding in the process of diagnosis by dispensing an exorbitant three dimensional image. CBCT not only be used in surgical fields, endodontics, prosthodontics, and orthodontics, for appropriate treatment planning and effective dental care, but also in forensics and radiotherapy. The clinical significance of this review is to update dental clinicians about CBCT applications in several fields of dental sciences.