The present intervention study showed that thoracoscopic-limited surgery for clinically early lung cancers depending on findings in preoperative HRCT is feasible and appropriate from the viewpoint of oncology.

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Objective and Methods. We retrospectively evaluated the differences of clinicopathological features and surgical outcome with regard to whether the lung cancer was detected by chest X-ray CXR without symptoms or by mainly respiratory symptoms. We classified 362 patients with lung cancer into 2 groups. In the mass screening and other disease group n 225 , their lung cancers were discovered by CXR mass screening or during medical examinations for other diseases. In the symptomatic group n 137 , their lung cancers were detected following the appearance of respiratory symptoms. Results. There was no significant difference in the age or gender between the two groups. Both tumor size and smoking index were lower, and pathological T1 pT1 disease, pathological N0 pN0 disease, partial resection or lobectomy, non-SCC squamous cell carcinoma and complete resection cases were more frequent in the mass screening and other disease group than in the symptomatic group p 0.01. A multivariate analysis of survival revealed that gender, smoking index, T-factor, N-factor, curativity and the detection method were significant 1 2

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