The research suggests that the root extract was significantly effective when compared with control and standard in the treatment of hyperlipidemia and hyperglycemia in diabetic rats. Therefore, it may be beneficial to diabetic patients.

Salvadora persica has been widely used for its reported biological activity in indigenous system of medicines. The main objective of the present investigation is to evaluate the analgesic activity of hydroalcoholic extract of Salvadora persica root on mice. Analgesic activity of hydro-alcoholic extract of Salvadora persica root at a dose of 100 mg/Kg, 200 mg /Kg and 400 mg /Kg were evaluated against drug pentazocine at a dose of 17.5 mg/Kg. Adult albino mice and rats of either sex of six numbers in each group were under taken for study and evaluated by eddy's hot plate and tail immersion method. The all doses of Salvadora persica root crude hydro-alcoholic extract were found to produce significant (P<0.05) analgesic activity. In eddy's hot plate and tail immersion, both method showed significant activity (P<0.05) after 30 minutes. The result showed significant analgesic activity against stimuli.

In the modern system of drug delivery, even after several efforts by the scientists, the chief key issue remains the efficient and effective amount of drug delivery at particular site. Due to the low residence time of API's at the required site, leads to the poor bioavailability of drugs in the conventional drug delivery systems. At present nanotechnology is the emerging field for delivery of drugs at size of nano-scale and very effective in sustained and targeted delivery of medicines i.e. polyplexes (DNA/polycation complexes), block copolymer micelles and nano-gels etc. In the human trials, polymeric micelles have been found to be very convincing method for delivery of anticancer drugs. Selection of suitable method of preparation remain an important aspect as particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamics properties of various types of drug molecules. Several methods to prepare polymeric nanoparticles have been developed and these techniques are classified according to whether the particle formation involves a polymerization reaction or nanoparticles form directly from a macromolecule or preformed polymer.