Ahara plays an important role in our life. Actually, our healthy life mainly depends on the different types of Ahara which we consume in our daily routine. So Acharya Charak mentioned Ahara in the three Upastambha of Ayurveda. Viruddha Ahara, or incompatible diet, is a very important issue discussed by ancient Ayurveda. The substances which are contrary to dhatus behave with Viruddha to them. This Viruddha Ahara may be in terms of properties, combination, processing, place, time, dose etc. or natural composition. The main aim of this review article is to compile and evaluate the concept of Viruddha Ahara. All the descriptions of Viruddha Ahara mentioned in different Ayurvedic texts were critically analyzed and discussed to check their relation. After critically analyzed it is concluded that if due to Viruddha Ahara, various types of diseases appear in our body, so we should take the Ahara according to Ayurvedic concepts mentioned in different Ayurvedic texts.

Ayurveda Samhita describes various types of Visha such as Sthavara Visha (Inanimate poison), Jangama Visha (Animate poison) and Kritima Visha. These types of Visha, when it enters into the body, it passes through the different Dhatus and give rise to different stages of Vega in the body and according to these Vegas, different types of signs and symptoms appear on the body. The main aim of this review article is to compile and evaluate the concept of Visha Vega and their sign & symptoms. All the descriptions of Visha Vega mentioned in different Ayurvedic texts were critically analyzed and discussed to check their relation. After analysis, it is observed that all the symptoms which appear during entering of the Visha are mainly due to their Vegas. As gradually stages of Vega progresses, their signs and symptoms gradually become more severe. After critically analyzed it is concluded that if we diagnosed the different Vegas of Visha  at the right time, we could treat those patients better.

Big data" is defined as the collection of large and complex datasets available in structured, semi structured, and unstructured form which are dif to process using traditional database management tools or data processing applications. Big Data is als defined from 5Vs which refers to Volume, Variety, Velocity, Veracity and Value .Clinical Research is one of the most important as well as promising part of health research. This article provides an overview on some specific aspects of clinical research adapted to Big Data Science path ways be utilized for transforming millions of data points into predictions & simulation to provide cost effective medicines in reduced timelines. This article also highlights the opportunities & challenges Data brings with it.