Bioenhancers or Bio potentiators are those agents which do not show any pharmacological action of their own at the therapeutic dose used, instead, they when combined with the active drug, lead to the potentiation of the pharmacological activity of the Drug. “Bioenhancing activity” is considered as a revolutionary concept that is being researched and tested in various modern medicines, but its roots, in general, has been obtained from a classical system of medicine called “Ayurveda”. In Ayurveda, the concepts which promote the mechanism of bio enhancing activity are of :- Yogavahi, Anupana, Bhaishajya kala, Rasayana, Various Yoga (Formulations), Purana Aushadhies, Penetration enhancers, Action augmenting drugs, Bhavana, and Process of Samshodhana. In this article, an attempt has been made to explain the concepts and mechanism of Yogavahi, and to throw light on the various drugs and processes mentioned in Ayurveda with Yogavahi property.

Kuchala (Strychnos nux-vomica) is spinal poison which is also classified as Upavisha in Ayurveda.Various poisons have been described in Ayurveda along with their antidotes. Mode of action of these antidotes is not mentioned in texts. In Ayurvedic literature According to Basavrajeeyam under the heading of Vish-Prativishani, Jambu (seed) have been described to be possessing antidote action which may act by some way to counter toxicity of Kuchala. It is necessary to verify the efficacy of these antidotes on scientific parameters so that it can be useful in emergencies. Objectives: To establish the action and mechanism of Jambu (seed) against toxic effects of Kuchala on albino wistar rats. Methods: albino wistar rats were selected as an animal model and antidote potential of Jambu (seed) against Kuchala is evaluated by measuring convulsions and histopathological reports of brain and spinal cord. Results: Jambu (seed) administration before Kuchala poisoning reduced the toxic effects of Kuchala such as convulsion and histopathological changes in brain and spinal cord. Conclusion: From this study, we can conclude that Jambu (seed) can resist the toxic effects of Kuchala up to some extent.

Introduction - Ayurveda a holistic system of medicine, originated in India more than 3000 yrs ago. The main objective of Ayurveda is to “Maintain the health of healthy person and to pacify the disease of a diseased person”. Immunity is the ability of the body to resist against the various foreign agents. The concept of immunity, in fact had been rooted in Ayurvedic system of medicine much before 600 BC. Material and Methods - In Ayurvedic classics Acharya’s has mentioned a lot of immune boosters, both single drugs and formulations. Ashwagandha, is one among them, which has got immense popularity recently, due to its ability to boost body immunity and also, it can increases body’s natural ability to fight viruses. Discussion- Ashwagandha, a special herb, used extensively in Ayurveda and is known for its capacity to boost the immunity. The pharmacodynamic action of Aswagandha itself proves the immunomodulatory effects. The herb is ushna in potency thereby reduces Kapha Vata, providing more strength to the immune system of our body. Being Madhura in rasa it provides ojas, bala and nourishment to the Dhatus. Conclusion- An effort to compile the details about Aswagandha in relation to its immune boosting power was done here.

Visha is another name for a chemical that depresses society. Visha is a material that is harmful to life and has properties like Aniedeshyarasa/Apaki, Vyavayi, Vikasi, Ushna, Teekshna, Ruksha, And Asukar. Garavisha is the name for synthetic poison, krutrima visha. These Gara vishas, depending on their combinations. Gara vishas, depending on their combinations, can cause illnesses like Shopha (edoema), Pandu (anaemia), Udara (ascites), Unmada (psychological disturbance), Durnam (piles), etc. in the body. Dooshivisha is the term for Sthavara, Jangama, or Krutrima poisons that are not completely eliminated from the body and become dry due to digestion (metabolism), antitoxic formulation, exposure to heat, air, or sunlight, or when the aforementioned natural ten qualities of the poison become less potent. In the present study we will investigate and apply the concepts of Agad Tantra to many ailments and pathological conditions, including Garavisha & Dooshivisha, using antitoxic formulations like Charakokta Vishaghana Mahakashaya.

Nidra (sleep) is one of the most important components of a healthy and satisfying life, according to Ayurveda. It is one of the three big subsidiary pillars (trayopastambhas) on which a person's health is firmly balanced. Acharya Vagbhata claims that 'Happiness and sadness, nourishment (perfect body) and abnormalities, strength and debility, sexual prowess and impotence, wisdom and ignorance, life and death - all depend on sleep'. Improper or excessive sleep, or sleep at an inappropriate time, vitiates all three doshas. Vitiated vata dosha causes giddiness, stiffness all over the body, restlessness, lack of concentration and decision-making power, excessive yawning, headache, etc. while vitiated pitta dosha mainly causes digestion-related problems. When the Kapha dosha is vitiated, it causes dullness and heaviness throughout the body, as well as tiredness. Getting enough good sleep at the right times can help you maintain your mental and physical health, as well as your quality of life and safety. In order to detach a tired mind from the senses, it is necessary to get the right amount and good quality of sleep. The quality of sleep can be harmed by partial disconnection of mind. Although most people are aware of the benefits of a healthy diet and regular exercise, they usually neglect the importance of sleep, which can have serious health effects