Faulty complete denture can lead to deleterious effects on residual ridges. These deleterious effects are further severed if patient is systematically compromised as in Diabetes mellitus. Decreased resistance to infection, vascular changes, and altered tissue response seen in uncontrolled Diabetes when coupled with faulty denture prosthesis can even lead to gangrenous necrosis. Prosthodontic management of edentulous patient with maxillary defect is a challenging task because there is reduced denture bearing surface compromising adhesion, cohesion and peripheral seal thus affecting retention adversely; reduced support area for denture; air leakage due to poor stability; retentive deficiencies and movement of prosthesis during function. Prosthetic rehabilitation for these patients can be accomplished with minor modifications in procedures like incremental shaping technique for taking impression, modifications in jaw relation, tooth arrangement, and fabrication of hollow bulb obturator along with atraumatic and meticulous care during all the procedures. This clinical report describes a case of gangrenous necrosis of premaxilla caused due to a faulty previous prosthesis; and its prosthodontic management.