Background:In the patients of cirrhosis oral health id generally poor and may lead oral infections. Periodontal disease is an infection of structures in mouth that surround the teeth, which is linked with several systemic diseases, including cirrhosis. Objective: To determine the frequency of Periodontitis in patients with cirrhosis at Chandka medical college hospital and Bibi Asifa dental college hospital Larkana.

Objective: To determine the soft tissue lip profile with Steiner (S) and Ricketts (E) lip analysis in patients with skeletal and dental class i occlusion at LUMHS Methodology: This descriptive study was done at department of Orthodontic, Liaquat University of medical and health sciences Jamshoro/Hyderabad, from august 2014 to august 2015. Individuals having age range of 18–30 years with dental and skeletal occlusion class I, competent lips involving facial profile, without history of preceding orthodontic treatment, mal and crowded aligned teeth and either of gender were included. To evaluate hard soft and tissue lip profile, the cephalometric analysis was done using radiographs, traced manually on matte acetate sheets with thicknesses of 0.003, measurements of 8x10 under direct inspection on an illuminator. SPSS version 26 was used for data analyzed. Results: A total of 100 patients were enrolled in the study their average age was 22±1.2 years. Males were 41% and females were 59%. The overall average of SNA angle was 81.866±1.199 and average of SNB angle was 80.667 ±1.27. Average of ANB angle, S line to upper lip, S line to the lower lip and E line to upper lip were 1.167 ±1.028, 1.067 ±1.006 mm, 1.917±1.369 mm, and 3.2±1.96 mm, respectively, while average of lower lip was 2.80+2.83. Conclusion: In terms of soft tissue lip profile with Ricketts (E) and Steiner (S) lip analysis among patients with dental and skeletal occlusion class I, the Antero-posterior position of lower and upper lip regarding E-line was 2.80 +2.83mm and 3.2+1.96 mm, respectively, and Antero-posterior position of lower and upper lip regarding S-line was 2.16+1.34mm and 1.30+1.019 mm, respectively. According to gender, there was statistically no significant variance. Keywords: Lip profile, skeletal, dental, occlusion class I