No abstract

Low molecular weight carboxylic acids are separated and quantitated by capillary zone electrophoresis (CZE) with an on-column conductivity detector. The addition of 0.2-0.5 mM TTAB (tetradecyltrimethylammonlum bromide) controls the electroosmotlc flow so that all carboxylate anions pass through the detector. Unlike other CZE detection methods, conductivity detection shows a direct relationship between retention time and peak area. This confers on conductivity detection, In CZE, the unique advantage that use of an Internal standard allows accurate determination of absolute concentrations In a mixture without separate calibration of response for each component.

No abstract

A new on-column conductivity detector tor use with capillary zone electrophoresis Is described. The system, constructed with Inexpensive, readily available components, can analyze nanolter samples. Peak area Is linear with concentration over

Electrophoretic separations carried out in capillary tubes offer the possibilities of rapid and automated analyses of small volumes of complex mixtures with unprecedented resolution and sensitivity. Some emerging developments of this new instrumentation are reviewed.