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Background:Chromohalobacter salexigens synthesizes and accumulates ectoines. Results: High ratio of the anaplerotic and catabolic fluxes involved in ectoines synthesis supports high biosynthetic fluxes at high salinity and leads to metabolite overflow at low salinity. Conclusion: Evolution optimized the metabolism of C. salexigens to support high production of ectoines. Significance: Metabolic adaptations in a compatible solute-accumulating halophile are described for the first time.

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Plastics have become an important environmental concern due to their durability and resistance to degradation. Out of all plastic materials, polyesters such as polyethylene terephthalate (PET) are amenable to biological degradation due to the action of microbial polyester hydrolases. The hydrolysis products obtained from PET can thereby be used for the synthesis of novel PET as well as become a potential carbon source for microorganisms. In addition, microorganisms and biomass can be used for the synthesis of the constituent monomers of PET from renewable sources. The combination of both biodegradation and biosynthesis would enable a completely circular bio-PET economy beyond the conventional recycling processes. Circular strategies like this could contribute to significantly decreasing the environmental impact of our dependence on this polymer. Here we review the efforts made towards turning PET into a viable feedstock for microbial transformations. We highlight current bottlenecks in degradation of the polymer and metabolism of the monomers, and we showcase fully biological or semisynthetic processes leading to the synthesis of PET from sustainable substrates.

This paper examines consensus building in AHP-group decision making from a Bayesian perspective. In accordance with the multicriteria procedural rationality paradigm, the methodology employed in this study permits the automatic identification, in a local context, of “agreement” and “disagreement” zones among the actors involved. This approach is based on the analysis of the pairwise comparison matrices provided by the actors themselves. In addition, the study integrates the attitudes of the actors implicated in the decision-making process and puts forward a number of semiautomatic initiatives for establishing consensus. This information is given to the actors as the first step in the negotiation processes. The knowledge obtained will be incorporated into the system via the learning process developed during the resolution of the problem. The proposed methodology, valid for the analysis of incomplete or imprecise pairwise comparison matrices, is illustrated by an example.