Citation:  Serrão Fensterseifer G, Lodi AP, Lima Dantas M, Boff AL, Lovatto L. Lentigo maligna of the face: the importance of clinical, dermoscopic, and histological correlation. Dermatol Pract Concept. 2019;9(4): 292-294. DOI: https://doi.org/10.5826/dpc.0904a08 Accepted: July 21, 2019; Published: October 31, 2019 Copyright: ©2019 Serrão Fensterseifer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: None. Competing interests: The authors have no conflicts of interest to disclose. Authorship: All authors have contributed significantly to this publication. Corresponding author:  Dr. Giovana Serrão Fensterseifer, Rua Professor Annes Dias, 135-Hospital Santa Clara, Santa Casa Porto Alegre, Brazil. Email: gfensterseifer@gmail.com

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Langerhans cell histiocytosis is a rare clonal proliferative disease, characterized by the infiltration of one or multiple organs by histiocytes. Due to the diversity of signs and symptoms, the diagnosis of this disease is often late. The estimated incidence in adults is one to two cases per million, but the disease is probably underdiagnosed in this population. This report presents a case of disseminated Langerhans cell histiocytosis. The authors highlight the most characteristic aspects of this rare and heterogeneous disease, which usually presents as a challenging clinical diagnosis.