Differential diagnosis of dermatoses presenting with skin fragilityand blisters in photo-exposed areas is broad and includes porphyrias, autoimmune bullous diseases (ABD), and phototoxicities such as pseudoporphyria. 1 Pseudoporphyria is a bullous photodermatosis with a clinical presentation and histology similar to that of porphyria cutanea tarda (PCT), although with no porphyrin increase. 1,2 Pseudoporphyria is infrequent (<150 reported cases), probably underdiagnosed/underreported, and can represent a diagnostic challenge. 1,2 Here, we present a series of cases with pseudoporphyria and propose a diagnostic algorithm.

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