Highlights d CCR5 is differentially upregulated in neurons after stroke d Knockdown of CCR5 induces motor recovery after stroke and improves cognition after TBI d Treatment with an FDA-approved drug, maraviroc induces recovery after stroke and TBI d Human carriers for CCR5delta32 have better outcomes after stroke

A 2-year 6-month male presented after an intrusive injury sustained at 15 months of age. Intra-oral radiographs showed coronal dilaceration of the germ of the permanent central incisor and the presence of a calcified tissue mass in the area of the trauma which was identified after surgical removal as the permanent upper left lateral incisor. Immediate treatment and long-term options are discussed.

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