The substances belonging to the class heterocyclic 1,3,5-triazinanes are extremely important because they stand out for the variety of biological activities, technological applications, such as insecticides, explosives and reagents for various organic reactions. In organic synthesis they are considered as being substances with simple preparation and low cost, which present an option for obtaining various other heterocyclic compounds, such as: imidazole, imine, aziridine, and diazirinamacrocycles.Keywords: Azoheterocycles; Synthesis; 1,3,5-Triazinanes; Formaldehyde. ResumoOs heterociclos da classe 1,3,5-triazinana são importantes por se destacarem pela grande variedade de atividades biológicas e aplicações tecnológicas, por exemplo, inseticidas, explosivos, e como reagentes para diversas reações orgânicas. Em síntese orgânica esse composto heterocíciclo se destaca por ser uma substância de simples preparação, custo baixo e que se apresenta como opção para obtenção de vários outros compostos heterociclos, como imidazol, imina, aziridina, diazirina e sistemas macrociclos.

SummaryA new and efficient method for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones in one step with high yields from the reaction of lawsone with 1,3,5-triazinanes was developed.

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The deposition or mineral scaling on surfaces is caused by the accumulation of inorganic salts. When it occurs in oil and gas production equipment, it causes major operational problems and severe damage to the pipes. Besides oil wells at sea, this phenomenon also occurs on the surface of membranes used in filtration, treatment and sulphate removal of sea water. Its origins lie in the incompatibility between the chemical composition of the formation and injection water or in the thermodynamic changes of system. These of the disadvantage can be prevented by the use of chemicals that act as scale inhibitors. This article discusses the origin of scale and its implications, and addresses the chemical classes, natural and synthetic, which are used as anti-fouling, as well as promising substances for this purpose.

Based on these results, we found that compound 12a promote ROS production, interfering with energy metabolism, cell viability and proliferation, and thus promoting an whole cell damage.