The clinico-pathologic spectrum ofleprosy in its diverse fo rms is the expression of the immunologic response of the human host to infection by My cobacterium leprae.In this spectrum, the ' lepromatous pole is characterized by a total lack of cell-mediated effector immunological responses; this lack is also seen to a lesser degree in borderline lepromatous (BL) as well as in other fo rms, which present a variable degree of deficiency of this type of immunity as they are located along the spectrum towards the tuberculoid pole of the disease.There is substantial evidence that the immunological defect which reaches its maximum expression in lepromatous patients is also present in other population groups, including a small portion of the healthy population. This evidence includes the fo llowing observations: (a) A significant proportion of patients with the indeterminate form of leprosy show immunological behaviour similar to that of the lepromatous patient, characterized by a lack of cell-mediated manifestations toward M. leprae. Without adequate treatment, this indeterminate form of leprosy shows a tendency to progress to lepromatous leprosy (LL). We have seen this phenomenon of progression towards the LL pole in indeterminate patients who, after many years of treatment, have stopped their medication due to various reasons and suddenly re-appear with LL or BL disease. On the other hand, indeterminate lesions in Mitsuda-positive patients show a tendency to regress spontaneously, or to evolve towards the highly resistant fo rms of the disease.' (b) Studies of the Mitsuda reaction in the general population, both in endemic and non-endemic areas, show that a small proportion of the general population is persistently Mitsuda-negative. In 1978 we studied the persist ence of this negativity towards lepromin in the population of a non-endemic area of Venezuela and found that 1·25% of the general population remained
De acuerdo a los resultados la fase de dilatación dura un promedio de 65'64" para vicuñas multíparas y de 72'50" para primerizas; La fase de expulsión del feto es de 19'79" para multíparas y de 22'25" para primerizas y la fase de expulsión de la placenta 61'21" para multíparas y de 62´00" para vicuñas primerizas. El tiempo promedio por parto es de 164'64" para multíparas y de 156'75" para vicuñas primerizas ocupando la fase intermedia el menor tiempo de las tres controladas. According to the results the dilatation phase last an average of 65'79'' for veteran mothers and 72'50'' for new mothers, the phase of the fetus expulsion last 19'79'' for veteran mothers and 22'25'' for new mothers the phase of placenta expulsion last 61'21'' for veteran mothers and 62'00'' for new mothers. The average time of the birth is 164'64'' for veteran mothers and 156'75'' for new mothers. The middle phase is the one that last less than the three that were studied.
En el año de 2018 y mediante los constantes patrullajes a nivel de campo en el Centro de Investigación, Producción y Transferencia Tecnológica de Tullpacancha - Huancavelica de la Universidad Alas Peruanas, se tomaron cinco muestras de fibra de crías de vicuñas las cuales fueron llevadas al Laboratorio de Fibras de la Facultad de Zootecnia de la Universidad Nacional Agraria La Molina, con la finalidad de determinar su longitud y diámetro de estas muestras obteniendo los siguientes resultados: Promedio Longitud: 2.90 cm. y 15.06 micras de diámetro.Estos resultados serán las causas por los cuales los cazadores furtivos no eliminan crías ya que el grosor de esta fibra es gruesa y por ello poco comercial.
La encefalitis autoinmune por anticuerpos antineurales de superficie, abarca un amplio espectro de entidades clínicas. La encefalitis por anticuerpos contra el antígeno de superficie de la porción externa del receptor del N-metil-D-aspartato (RNMDA) es la más frecuente y de mejor caracterización. Se reporta el caso de un adolescente con un cuadro clínico neurosiquiátrico y crisis epilépticas de reciente inicio, que presentó respuesta positiva para anticuerpos anti-RNMDA y respuesta parcial a tratamiento con corticoterapia e inmunoglobulina; en vista de esto, recibió manejo adicional con recambio plasmático seguido por terapia de mantenimiento con ciclos de inmunoglobulina, sin uso de inmunosupresores. Se reportan los resultados del seguimiento a largo plazo.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.