These results suggest that in ACC galectin-3 may play a role in cellular proliferation through cyclin D1 activation. In addition, nuclear expression of galectin-3 in ACC may be related to a more aggressive behavior of this lesion. Although beta-catenin seems to play a role in carcinogenesis in both lesions, it seems that it does not bind to galectin-3 for cyclin D1 stimulation.

Background The prophylactic extraction of third molars is a common practice in dental offices, but divergent opinions are found in the literature regarding the indication of this procedure. The aim of the present study was to determine the prevalence of pathological changes associated with the pericoronal tissue of asymptomatic impacted third molars that could justify prophylactic extraction. Materials and Methods A cross-sectional observational study was conducted in which 109 pericoronal tissues with no radiographic evidence of pathology were histopathologically analyzed. The specimens were fixed in 10% formalin, embedded in paraffin, stained with hematoxylin and eosin and analyzed individually by two pathologists. Result The frequency of inflammatory infiltrate in the dental follicle of patients older than 20 years of age was significantly higher than that of younger patients (p = 0.004), demonstrating an association between inflammation in the dental follicle and patient age. The occurrence of squamous metaplasia was also greater in patients older than 20 years (p = 0.042), demonstrating that the prevalence of squamous metaplasia increases with age. A significant association was also found between inflammation and squamous metaplasia (p \ 0.001). Conclusion Pathological changes may be present in the dental follicle of impacted third molars even in the absence of clinical or radiographic signs of disease.

The autors present a report of a case of about hairy leukoplakia that have relationship with a HIV seropositive patient. We will discuss the clinicar and histopathoiogical aspects of these lesions. It is stressed the role of the dentist in the of AIDS related oral lesions.

Os autores apresentam um caso clínico de fibroma ossificante em paciente de 46 anos de idade. São discutidos a etiopatogenia, aspectos clínicos, radiográficos e microscópicos e diagnóstico diferencial.