RESUMO
O propofol em nanoemulsão é uma nova formulação constituída por sistemas nanoemulsionados, caracterizado pela ausência do veículo lipídico. A modifi cação do veículo pode 2, 5, 10, 15, 30, and 60 minutes after the bolus dose, and after the end of the infusion at fi ve, 10, 15, 30, 60, and 90 minutes and 2, 3, 4, 6, 10, and 24 hours. There were no signifi cant differences in the evaluated pharmacokinetics parameters that included volume of distribution, clearance, elimination rate constant, half-life, and distribution constants, demonstrating that propofol nanoemulsion has no pharmacokinetics differences when compared to the traditional formulation.
RESUMO
O objetivo deste estudo foi comparar os efeitos clínicos da indução com propofol em nanoemulsão e em emulsão lipídica em gatas, após repetidas administrações. Utilizaram
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