No abstract

Carboxylic acid esters Q 0530 Antioxidant and Antimicrobial Activity Evaluation of Polyhydroxycinnamic Acid Ester Derivatives. -A variety of title hydroxycinnamates [cf. (VIII), (IX), 16 examples] which show significant antioxidant activity is synthesized. The butyl esters of the cinnamic acids, especially (IX), exhibit strong antimicrobial effects. -(VENKATESWARLU, S.; RAMACHANDRA, M. S.; KRISHNARAJU, A. V.; TRIMURTULU, G.; SUBBARAJU*, G. V.; Indian J.

Synthesis and Antioxidant Activity of Hispolon, a Yellow Pigment from Inonotus hispidius.-Hispolon (IV), a recently isolated natural hexa-3,5-dien-2-one, is synthesized for the first time. It shows strong antioxidant and weak antibacterial activities. -(VENKATESWARLU, S.; RAMACHAN-DRA, M. S.; SETHURAMU, K.; SUBBARAJU, GOTTUMUKKALA V.; Indian J.

Synthesis of novel caffeic acid esters (1 and 2) was accomplished starting from appropriately substituted benzaldehydes (3 and 9). While compound 2 exhibited potent anti-oxidative activity in both the nitroblue tetrazolium and 1,1-diphenyl-2-picrylhydrazyl radical-scavenging models, compound 1 showed moderate 5-lipoxygenase inhibitory activity.

A general and staight forward total synthesis of 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadiene-5-one (5) starting from 4-methoxycinnamic acid (6) via ethyl 5-(4-methoxyphenyl)-3-hydroxy-2.4-pentadienoate (14) was accomplished in 19% overall yield.