The ICG fluorescence-guided SLNB is an innovative imaging technique for dermato-oncology, reliable and providing additional information in the detection of SLN. Therefore SLNB with fluorescence-dye is an attractive option with intraoperative real-time lymphoscintigraphy to improve the detection of SLN in cutaneous malignancies and potential reduction of the false negative rate in SLN.

Although S. aureus is still the most frequently detected bacterium in our wound care center, there has been a shift in the bacterial spectrum from gram-positive towards gram-negative bacteria over the last decade.

The onset of chronic leg ulcers caused by CVI and mixed arterial and venous disorders in our patient population showed significant seasonal variations and demonstrated an inverse relationship to temperature. In summary, climatic factors appear to play an important role in the onset of chronic leg ulcers. Climatic factors may therefore need consideration in future clinical investigations and in the development of prophylactic therapeutic strategies.

Major components in the conservative treatment of patients with chronic venous leg ulcers are compression therapy and modern wound dressings. Both therapies are used simultaneously. Consequently it is important to know the exudate capacity of modern wound dressings changes during compression therapy. In the first part of our study we analyzed the maximum exudate capacity of 15 modern wound dressings. In the second part we showed that under compression stockings of class 2, a reduction of 44.08% and under compression stockings of class 3, a reduction of 50.49% occurred. In the third part we pointed out that all the investigated wound dressings released absorbed fluid when under compression. Again the effect was higher when using compression class 3 with 40.78% compared to compression class 2 with 40.50%. Our results show for the first time the broad variability of exudate capacity of modern wound dressings. Our results show that compression therapy has a considerable effect on the ability of modern wound dressings to absorb and retain exudate and suggests that more frequent changes may be required.

The results of the study demonstrate that Tegaderm™ Matrix along with treatment of underlying causes is a well tolerated wound dressing promoting wound size reduction up to healing for the majority of patients with previously therapy-refractory chronic wounds.