Many non-ambulatory children with cerebral palsy (CP) who are indicated for hip reconstruction and/or spine surgery are medically complex and thus high-risk surgical candidates. A well-coordinated, multidisciplinary team approach for these individuals is essential to reduce the risk of perioperative complications. This review offers an evidence-based overview covering interventions that have been shown to improve safety and outcomes after hip and spine surgery in non-ambulatory patients with CP. Specifically, this review will focus on the team approach to perioperative care coordination with the goals of optimizing medical and nutritional status, reducing postoperative complications, and improving patient and family satisfaction. Further, this review will highlight the associated care pathway utilized at Nemours Children's Health-Delaware, in addition to highlighting key measures that may be adopted by other institutions to help foster organizational cultures that prioritize family-centered care. Key Concepts• Nonambulatory children with CP commonly develop significant hip and spinal deformity which can be considered for extensive reconstruction.• It is important to identify co-morbid medical conditions as well as psychosocial factors for both patients and caregivers as these may contribute significantly to outcome.