Outbreak of fungemias by Sarocladium kiliense in eight public hospitals per intrinsic contamination of ondansetron intravenous Sarocladium kiliense is a saprophyte fungus that can cause opportunistic infections associated to invasive procedures. We report a multi-hospital nosocomial outbreak of fungemias due to this agent. Patients with positive blood culture to this agent were studied after six bloodstream infections identified in three Chilean hospitals in July 2013 were reported to Ministry of Health National Infection and Prevention Control Program. In general, there were mild clinical manifestations, without deaths attributable to the infection. Epidemiological and microbiological study identified 65 cases in 8 hospitals, mostly pediatric patients in chemotherapy. Initial studies of 94 different drugs and medical devices had negative results, until a second analysis of specific blisters and their pharmaceutical matrix selected by epidemiological criteria identified an intrinsic contamination of ondansetron blisters from a specific producer used in all the patients. A recall of contaminated ondansetron blisters was performed in all the country, after which the outbreak was contained. Surveillance and response of local and national infection prevention and control programs and laboratory support were key to control of a national multi-hospital common source outbreak due to contamination of a drug by an unusual fungus.

El presente trabajo tiene por objeto la investigación que mide la actitud hacia el estudio de la asignatura de estadística dentro de su formación académica y militar, y cómo incide en el campo profesional los conocimientos obtenidos en la ESMA. El método utilizado para el desarrollo de la investigación tiene relación directa con el enfoque cuantitativo que utiliza como herramienta la técnica de la encuestaAuzmendi (1992), aplicada a una muestra de 219 personas, entre hombres y mujeres, objeto de investigación, en edades comprendidas de 18 a 25 años. Para poder determinar los factores se aplicó la técnica estadística de análisis factorial, para lo cual se debe observarprimero los valores que tienen la Prueba de Esfericidad de Barltlett y el Índice Kaiser Meyer Olkin (KMO), los mismo que dieron como resultado 0.000 y 0.903 respectivamente una vez eliminada la variable "Para el desarrollo profesional de nuestra carrera considero que existen otras asignaturas más importantes que la estadística" que de acuerdo a la Matriz de Correlación Anti Imagen obtuvoel valor más bajo, 0.618. Lo cual indica que es bueno utilizar Análisis Factorial para el estudio, obteniendo los siguientes factores: Ansiedad, Importancia, Utilidad, Deseo de Saber y Diversión.

This paper aims to analyze the negotiations between the Andean Community of Nations and the European Union and the impact on the Ecuadorian trade balance from 2000 to 2010, taking into account that since Ecuador becomes a member of the then called the Andean Pact, now Community of Andean Nations, various economic benefits obtained as an increase in terms of local recognition and bargaining power, although stocks of information asymmetries and shortcomings of its productive apparatus. In the field of international negotiations, it has to be in terms of trade, the EU is the second most important partner of the Andean Community of Nations according to statistics figures of recent years, and this relative importance began from the previous decade. That is why trade relations between Ecuador and the European Union and its impact on Ecuador's trade balance will be analyzed, along with the trade balance between Ecuador and the Andean Community of Nations, where an econometric analysis using cointegration between balance is made commercial and trade balance of Ecuador Andean Community of Nations European Union, an analysis of impulse response function Ecuador's trade balance. Demonstrating empirically the impact of the agreements between these integration blocs in the trade balance of Ecuador, to propose corrective measures medium to long term.

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