Multi-element analysis and differentiation of Chilean wines using mineral composition and multivariate statistics. 2018. Cien. Inv. Agr. 45(2): 181-191. The concentration of seventeen metal elements was analyzed in 130 commercial samples of Chilean wines, using flame atomic absorption spectroscopy (AAS) and inductively coupled plasma-mass spectrometry (ICP-MS). The elements analyzed were within the usual concentration ranges previously reported in other wine regions (for example: Fe, 2.08 ± 0.99 mgL-1 ; Zn, 0.71 ± 0.44 mg L-1 ; K, 788± 219 mg L-1 ; and Na, 14.62 ± 8.6 mg L-1). When the metal content of the samples was compared among geographic areas, significant differences in the concentration of K, Na, Mn, Mg, Zn, and Cr were observed (p ≤ 0.05). Moreover, principal component and linear discriminant analyses, used to discriminate wines according to geographic area, obtained adjustments above 90% for white wines and over 70% for red wines.