Objectives: To determine ultrasonic and dopplerometric characteristics of chronic endometritis of women having reproductive problems before and after offered treatment. Materials: We have examined 56 patients (the first group) having morphologically verified chronic endometritis and 42 healthy women (the second group) without pregnancy and endometrial interferences in anamnesis. Everybody has been carried out common research such as anamnesis, general and gynecological examination, ultrasonography, dopplerometry. We have also conducted morphological and immunohistochemical research of endometrium's tissue and have taken bacterial seeding from uterine cavity. Patients of the first group received treatment, after this treatment, we have conducted the control ultrasonography and dopplerometry. Results: Women of the first group have disturbance of endometrium's ultrasonic structure and modification of bloodstream in the fallopian, radial, basale and spiral arteries. After the treatment, the patients with chronic endometritis have an improvement of endometrium's structure and thickness and in the characteristics of bloodstream. Conclusions: Each woman with chronic endometritis has a modification in ultrasonic and sanguimotory factors of endometrium. With the purpose of determination of the endometrium's state on stage of pre-gravity training sonography and dopplerometry are the necessary methods of research. Offered method is effective in the treatment of chronic endometritis.

Reflections and the 'De Régnon Paradigm': A Probe into Recovering the Social-Trinitarian Emphases of the Cappadocian Fathers. The article examines the so-called «Social model of the Trinity» and its implications for theology, religious anthropology, and ecclesiology in its social dimension. The Trinitarian approach of the Cappadocian Fathers is lifted up as a potential source of inspiration for a more complex and dynamic understanding of the Trinity in the West, urging the West to learn from and integrate critically its valuable emphases. The article is constructively critical to the Latin philosophical-theological approach to the definition of the Trinity, suggesting, however, that the commonly accepted 'de Régnon Paradigm' among most Western scholars does not reflect de Régnon's original intentions and does not do justice to the natural affinity and even overlapping of ideas and emphases between the socalled 'Latin' and 'Greek' approaches to the philosophical-theological question of the Trinity.

Статья посвящена вопросам трансформации национальной идентичности Великобритании, составным элементом которой является евроскептицизм, в условиях продолжающихся переговоров Лондона и Брюсселя по выходу страны из Евросоюза. Делаются выводы о том, что, несмотря на частичное удовлетворение требований сторонников Брекзита в ходе первого раунда переговоров, страна расколота и вопрос о будущем коллективного самосознания Британии остается открытым.

Introduction. The high level of trade, population migration, and changes in the infrastructure of economic activity in the regions created the prerequisites for the dispersal and adaptation of parasitic pathogens to new factors, including adverse environmental and climatic conditions of their circulation. For the first time on the example of the distribution of long-term average incidence rates among the four most common parasitic nosological forms, the etiological factor of which is the causative agents of different taxonomic groups, systematized by the type of their circulation in various environmental objects: ascariasis (soil), enterobiosis (household items), opisthorchiasis (fish, products processing), echinococcosis (soil, water, contact with sick animals, processed products of animal raw materials. At the same time, a high level of soil contamination resistance (42.1%), surface runoff (41.8%), surface water (42.5%), sewage sludge (35.1%) characterizes the resistance of the parasitic system to the effects of the existing anthropogenic press on the causative agents of helminth and protozoal infestations and indicates the maintenance of active circulation of pathogens in the environment. Material and methods. The analysis of the average long-term level of parasitic morbidity and changes in the boundaries of the territorial distribution of parasitoses over the past 10 years (2009-2018) in 85 administrative units of the Russian Federation. The epidemiological development trend is determined by the methods of ranking the dynamic series of incidence with categorization by levels relative to the average Russian indices of parasitic incidence and calculation of the linear trend. Results. The calculation data are plotted on the administrative-territorial map of Russia with the help of a GIS program (MapInfo Pro 16) with the allocation of SMPZ levels for each nosology - single, low, medium, high, super high. Conclusion. Calculations of the development of linear trends of medium and low levels, as well as single cases of morbidity, were shown to allow differentiating the development trend of the epidemic process and draw prognostic conclusions.

Introduction. Modern parasitology is an area of interdisciplinary research that uses the methods and approaches of various biological disciplines, such as genomics, proteomics, bioinformatics, ecology, biology, medicine, veterinary medicine, climatology, using methods of landscape-geographical mapping, mathematical modeling to assess the parasitological situation and predict its dynamics. New problems associated with the parasitic aspects of global climate change, the introduction of new host species and parasites (pathogens), and anthropogenic transformation of natural ecosystems become topical. In this regard, the primary tasks for optimizing the socio-hygienic monitoring of the parasitic safety of the environment is the introduction of new methodological approaches for ranking territories - the risk according to the species composition and intensity of circulation of pathogens of parasitic diseases, the trend in changes in their range of pathogens and epidemiological properties in anthropogenically determined conditions. The purpose of the study is to substantiate the methodology for choosing a territory for optimizing social and hygienic monitoring and substantiating proposals for the unification of hygienic standards for parasitological indicators of environmental safety. Materials and methods. Experimental parasitological monitoring was carried out at the pilot site. 712 samples were studied using unified methods of parasitological research of biomaterial (MUK 4.2.3145-13 “Laboratory diagnostics of helminthiases and protozooses”) and environmental objects (MUK 4.2.2661-10 “Methods of sanitary and parasitological research”). Results. Data were obtained on the high intensity of the circulation of pathogens of parasitic diseases in the environment - 25%. More than 15 types of pathogens of parasitic diseases have been systematized. Limitations. The limitations of the study were associated with the lack of development of diagnostic tools for the genetic identification of parasitic pathogens within the same systematic group by PCR analysis. Conclusion. Methodological disagreements in various normative documents to the composition of the “target indicators” of research are determined. The practical part of the work included the collection of material from people and animals, from environmental objects. A new approach to the hygienic standardization of parasitological indicators based on group systematization of the propagative stages of development of parasites with subsequent methodological determination of their taxonomic affiliation is substantiated.