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Objective-To compare the three-dimensional (3D) linear displacements and the mesiodistal and buccolingual angulation changes after orthodontic treatment in digital dental models (DDMs) and 3D models derived from cone-beam computed tomography (CBCT). Settings and Sample Population-Digital dental model and CBCT scans were selected from 24 adults who had undergone orthodontic treatment for mandibular anterior crowding. Material and Methods-3D linear displacements and changes in angular measurements (mesiodistal and buccolingual angulation) were assessed in pre-and posttreatment DDM and CBCT images using the software ITK-snap and 3D SlicerCMF. Intra-and inter-rater agreement of measurements in DDM and CBCT were tested using the intraclass correlation coefficient (ICC).