ResumenEn pocientes ralieddcs por sindrome de mue^e subita infartil se ban describe alteraciones de la maduracion neuronal en el tronco cerebra' y gliosis. Propos'io: determine' si existen alte'accnes en ninos foilecidos per sind'ome de muerte subita infantil. Su/etos y metodo~ mediciones de densidad, longitud y voLmen del cilindro dencrilco de las celulas piramidales en prepcraciones de la co rt eza motora de cuatro lactantes fallecidos por sindrcme de muerte sub'ta infantil y cuatro con'roles muertos per neumcnia. Lcs preparaciones fuercn teridas con la tecnica de Golgi-Cox y evaluadas con rnetodos morfometricos. Resuilados' no se encontrarcn diferencias s'gnificativas e~ la densidad, nCmero de rarnas dendritlcas a diferentes distancias eel soma neu'onal y volumen del cilrdro dendritico basal entre los 'actantes faliecidos por neurnonia y los considerados ccmo ccsos de muerte sCbita infanril, pero en estos Cltimos se "ecistro, a diferenca de los cent roles, rnarcoda proliferaclon ce la glia. Concius/or,: en lactantes rallecicos por sindrome de muerte subita la madurac'on neuronal podria no ser afectada per aquellos factores que, e 1 -cambio, .nducirian un retcrdo de la mac'uracion histologica de nucleos del tronco encefalico y clics's difusa del tejico ne'vioso. La gliosis sugiere exposicio-" cronico c situaciones de hipoxic IPalabras clave: muerte siibitc infantil, denc'ritas, neocorteza.] Neocortical pyramidal cell dendritic development in victims of the sudden infant death syndromeDelayed h'stolocica: mcturation o 1 oral-"-stem ganglia and gliosis of t~e neural tissues hcs been cescribed "n sudde n infant death syndrome victims. Objective: to compare 'he basal dendr'tic arborization pattern of ! arge pyramidal eels o* t-ie primar/ motor cortex in sudaen infant death syndrome (5DS) victims and patients whose death was not SIDS. Subjects and methods: dendritic density 1 of giant pyramidal cells at Icyer IV [Brodmann] of brains from four infants that d'ed of SIDS were examined by mea^s of the Golgi-Cox rinct'cn and morphomet'ic 1 ' methods end compared with that of another four infants whose death was djs to pneumonia. Results: Dend'itic length, cylincHc volume and density-were simila-in bo'h SIDS and Non SIDS victims. Marked clial proliferation was seen in the ceeper cortical layers iBrodmann's V and Vt| of S'DS compared to Non SIDS victims brains. Conclusion: this findings probably indicate that factors inducing delayed brcirsrern neuronal maturation, and central nervous tissues gl'os ; s, in patients rha: eventually die of SIDS, do not influence neuronal maturatio^ of the motor cortex, ixtensive gl'os ; s in these cases suggests chronic exposure to hipoxia before death.(Key words: sudden infant death syndrome., dencrites, necccr^ex.)1. Cirujano dentista.
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