The Department of Ñeembucú is one of the least well-documented areas of eastern Paraguay, and the flora is composed of a mixture of forest and Chaco elements. Regions like Ñeembucú are often considered of lower diversity and interest that more forested regions; this results from both actual species richness figures and from under-collecting due to perception as uninteresting. We present here a checklist of the vascular plants of Ñeembucú, which includes 676 taxa (including infraspecific taxa and collections identified only to genus) in 100 families and 374 genera. Four hundred and thirty nine (439) of these are new records for Ñeembucú and of these, 4 are new published records for Paraguay. Synonyms, distribution details within Paraguay and a voucher specimen or literature record are provided for each taxon, and a brief analysis of the diversity and importance of the flora is presented.

Paraguay, a country whose economy is based mainly on agriculture and livestock for export, has experienced a major expansion in mechanized crops during the last few decades. Despite being heavily dependent on agriculture, Paraguay has very limited research on crop weeds, in spite of these having a high economic impact on production. This work aims to update and enhance the knowledgebase on the most common weeds affecting productive fields throughout the different ecoregions of Paraguay. We present here the first checklist of crop weeds for the country, which includes a total of 256 taxa (189 species, 10 subspecies, 54 varieties and 3 forms), with the most species-rich families being Poaceae and Asteraceae followed by Malvaceae, Amaranthaceae, Fabaceae and Solanaceae. The list includes three new records for the country. Synonyms, distribution details within Paraguay, habit and a voucher specimen are provided for each taxon.

We present a list of endemic plants of Paraguay, which includes 374 taxa from 52 families and 162 genera based on the revision of primary data (herbarium collections). Synonyms, habit, distribution in Paraguay and all the voucher specimens seen or cited in recent bibliographies or in the consulted databases are provided for each taxon. A brief analysis of the diversity and importance of this endemic flora is presented. A list of excluded species, which were considered as endemics in previous publications, is also included.

Manihot takape De Egea & Peña-Chocarro, sp. nov. is described and illustrated as a new species from the Paraguayan Chaco. It was collected while carrying out fieldwork related to the study of the most important Wild Crop Relatives of the country’s flora. Morphological characteristics that differentiate this species from closely related taxa, as well as its habitat, geographical distribution and conservation status are provided.

Cissampelos andromorpha DC. y C. arenicolaM. Nee & R. Ortiz se citan por primera vez para la flora Argentina. Se presentan descripciones e imágenes de pliegos de herbario de las especies mencionadas y se actualizan sus distribuciones geográficas. Se incluye una clave para la identificación de las cuatro especies de Cissampelospresentes en Argentina