Acute lymphoblastic leukemia (ALL) is a malignat disease that at most was suffered by children. Mothers of children with ALL suffer from prolonged anxiety due to the prolonged treatment of ALL (approximately two years) with a relatively expensive cost. Anxiety is a uncomfortable feeling that appears if someone is dealing with difficult problems. Symptoms of anxiety include heart palpitation, trembling, difficulty in concentrating, excessive sweating, and rapid breathing. This was a descriptive quantitative study with a cross sectional approach. In this study, we used HARS instrument and data were processed by using SPSS 20. The results showed that 30% respondents had mild anxiety, 26.7% had medium anxiety, 26.7% had severe anxiety, and 16.7% did not have anxiety. Conclusion: In this study, most of the respondents had mild anxiety, followed by mild and severe anxiety. However, some respondents did not suffer from anxiety.Keywords: anxiety, mothers of children with acute lymphoblastic leukemia, HARSAbstrak: Leukemia limfoblastik akut (LLA) merupakan penyakit keganasan yang paling banyak diderita oleh anak. Penyakit leukemia limfoblastik akut yang diderita oleh anak memberikan dampak kecemasan yang berkepanjangan pada Ibu. Hal ini disebabkan oleh protokol pengobatan yang lama yaitu kurang lebih 2 tahun, dengan biaya yang tergolong mahal. Kecemasan adalah perasaan tidak nyaman yang muncul jika seseorang berhadapan dengan masalah yang berat. Gejala kecemasan diantaranya jantung berdebar, gemetar, sulit berkonsentrasi, keringat berlebihan, dan pernapasan cepat. Penelitian ini bersifat deskriptif kuantitatif dengan pendekatan potong lintang. Penelitian ini menggunakan instrumen HARS dan data yang diperoleh diolah menggunakan SPSS 20. Hasil penelitian menunjukkan sebanyak 30% responden mengalami kecemasan ringan, 26,7% dengan kecemasan sedang, 26,7% dengan kecemasan berat, sedangkan 16,7% responden tidak mengalami kecemasan. Simpulan: Pada penelitian ini didapatkan responden terbanyak mengalami kecemasan ringan, diikuti oleh kecemasan sedang dan berat. Sebagian kecil responden tidak mengalami kecemasan.Kata kunci: kecemasan, ibu yang anaknya menderita LLA, HARS
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