Alveolar recruitment is not protective against hyperinflation of the baby lung because lung parenchyma is inhomogeneous during ventilation with the open lung strategy.

In this model, the end-inspiratory transpulmonary open lung approach minimized the impact of chest wall stiffening on alveolar recruitment without causing hemodynamic impairment.

We would like to thank you very much for the thoughtful and constructive review of our paper.We have carefully read the comments made by the Editor and Reviewers and we agree that suggestions have been substantial in both clarifying and improving the scientific message coming from this experience. Thus, by replying point-by-point to the Editors' and Reviewers' letters, we have modified the revised manuscript accordingly. Please find a marked and clean copy of the revised manuscript.While we hope that you could find the revised version of the manuscript acceptable for publication as "Research" in Minerva Anestesiologica we will be happy to further respond to any comments and questions, should they occur.

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