Salviarin has been shown by a combination of spectroscopic and X-ray methods t o be 15.1 6-epoxy-trans-cleroda-2.1 3(1 6), 14-trieno-l2.17;19,18-dilactone (1) Salvia species (Labiatae) are widespread in both the temperate and the tropical zones and a number have found local use as medicinal and culinary herbs.l A variety of bi-and tri-cyclic diterpenoids have been isolated from these species. Salvia splendens is a Brazilian species which is now widely used for ornamental purposes. Extraction of the leaves has afforded ursolic p &o I ' tHz 1 ' ' 0 acid and a new diterpenoid, salviarin, C2,H2,05, to which we assign structure (1) .t This had i.r. absorptions characteristic of a y-lactone (1 775 cm-l), a 6-lactone
Two new compounds, 2,5-dihydroxyisocostic acid and 2,3-dihydroxycostic acid together with three known sesquiterpene compounds, Isocostic acid, Carabrone and Tomentosin, have been isolated from the acetone extract of Inula viscosa (L.) Aiton. The structures of all new compounds were determined by spectroscopic methods, in particular 1D and 2D (1)H- and (13)C-NMR. The (13)C-NMR spectra of Isocostic acid and of Tomentosin are reported here for the first time.
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